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从1994年 FGFR3靶点被证实与ACH相关，到2021年Vosoritide获批上市，ACH患者等待了近30年，才迎来首款针对性治疗药物。而随着Infigratinib叩响上市的大门，以及身后一众迭代疗法的逼近，ACH精准治疗的新大门正加速开启。这也是罕见病从被行业忽略到逐渐被重视的真实缩影。
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This almost certainly won’t happen to the ISS. At the same time, it’s a far more extreme version of the only way an American space station has ever come down. In 1979, after years spent vacant in orbit, Skylab, the US’s first space station, started sinking toward the atmosphere, where it threatened to fall and drop molten spacecraft parts on Earth. At that point, NASA officials had to remotely wake up its computers and, with only limited control of the station, direct it over a location that would endanger the fewest humans.